The Relationship Of Blood Pressure With Plasma Atherogenic Index In Type 2 Diabetes Mellitus Patients

Research Article
Sümeyra Alan YALIM and Zafer YALIM
DOI: 
http://dx.doi.org/10.24327/ijrsr.2019.1003.3272
Subject: 
science
KeyWords: 
Diyabetes Mellutus, Hypertension, Plasma atherogenic index
Abstract: 

Objective: Type 2 Diabetes Mellutus (T2DM) patients have the abnormal distribution of body fat and a high visceral fat area, which was associated with plasma atherogenic index (PAI). PAI is a valuable marker for the cardiovascular disease and cardiac risk. The aim of this study was to evaluate the role and clinical use of PAI in the cardiac risk in hypertensive T2DM patients compared to normotensive T2DM. Methods: A total of 124 patients were included in the study. The patients were separated two groups that normotensive T2DM (n: 58) and hypertensive T2DM (n: 66). PAI was measured as a logarithmic value of triglyceride to high-density cholesterol ratio. Baseline demographic and clinical characteristics of patients were recorded and by used automated soft ware and compared between the groups. Results: Some demographic variables of the groups were similar in our study (such as age, gender, smoker, presence of chronic disease, fasting glucose and hemoglobin A1C). Lipid profile, PAİ and systolic and diastolic blood pressure significantly impaired in hypertensive group (p<0,005). Also, we found that a significant relationship between blood pressure and PAİ used the corelation analysis (p<0,001). Conclusion: Hypertension and diyabetes mellutus are two major risk factors for cardiovasculer morbidity and mortality. Epidemiological evidence shows the frequent association between hypertension and T2DM. In our study, we showed that PAI values were higher in hypertensive T2DM patients compared to normotansive T2DM patients. According to the correlation analysis, there was a positive correlation between the PAI levels and blood pressure in hypertensive T2DM patients.