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The aim of our study was to evaluate the importance of esophageal manometry in case of patients with reflux symptoms, non organic dysphagia and noncardiac chest pain (NCP). Our study included 255 patients, of which 155 were with reflux symptoms, 38 patients with dysphagia and 62 with NCP. The patients with reflux symptoms, presented with heart burn with regurgitation (61.29%), heart burn with dysphagia (7.74%), only heart burn (19.35%) and atypical symptoms (11.61%).After exclusion of organic diseases related to esophagus and heart esophageal manometry were done. Manometry showed abnormalities in 54.83%, 68.42% and 38.70% of patients with reflux, dysphagia and NCP respectively. In reflux group, most common were Hypoperistalsis (22%) followed by Hypotensive LES (29.67%). In dysphagia group, most common were achalasia cardia (55.26%), whereas, in case of NCP, Hypotensive LES (24.19%). So esophageal manometry should be first order of choice in patients with reflux symptoms, dysphagia and NCP after exclusion of all esophageal and cardiac organic disease to detect abnormalities in esophageal muscles as well as lower esophageal sphincter pressure, so that the patients can try to modify their life style.