Retroperitoneal masses are one of the diagnostic challenges. Multidetector computed tomography (MDCT) is considered as ideal imaging modality in evaluating the retroperitoneal masses. The objective of this study was to locate, differentiate and diagnose the retroperitoneal masses. It is a prospective study where72 patients were evaluated at JJMMC, Davangere over a period of 2 years from October 2016 to October 2018.Out of the 72 cases of retroperitoneal masses, 23 cases (32%) were primary retroperitoneal mass lesions. Further, out of the 49 cases (68%) of masses arising from retroperitoneal organs, 19% were of pancreatic origin, 17 % of renal origin, 12 % adrenal origin and 2% of aortic origin. The present study concludes that using MDCT it is possible to localise, differentiate and diagnose the retroperitoneal masses. Based on characteristic features and relevant clinical information narrowing of differential diagnosis is possible.
