Rosai Dorfman Syndrome – Diagnosis On Fine Needle Aspiration Cytology With Review Of Literature

Rosai-Dorfman disease, also referred to as Sinus histiocytosis with massive lymphadenopathy, is a rare non neoplastic proliferative disorder of the cells of macrophage-histiocyte family that was first described by Destombes in 1965. As per review of literature there are only few reports or small series cases on the (FNA) cytologic features of this entity. We report a case of Rosai-Dorfman disease presenting with massive bilateral cervical lymphadenopathy and conclude that FNAC is useful and reliable tool for diagnosis of Rosai-Dorfman disease avoiding the need of biopsy and proceed with accurate treatment and management of the patient.