A Screening Strategy Of Lipid Profile In Young Patients

Research Article
Jamil-ul-Hussain., Vikrant Singh and Vanita Gupta
DOI: 
http://dx.doi.org/10.24327/ijrsr.2018.0908.2491
Subject: 
science
KeyWords: 
Cholesterol, triglyceride, lipid
Abstract: 

Introduction: Certain patterns of blood lipids including elevated total cholesterol (TC), elevated low-density lipoprotein cholesterol (LDL), and low levels of high-density lipoprotein (HDL) cholesterol are important risk factors for coronary heart disease (CHD). Because of the important health impact of CHD and the role of lipid disorders in its development, routine universal or targeted screening for lipid disorders has been advocated. Material and methods: The present study was conducted randomly in 50 young adult patients less than 40 years of age in Department of medicine at a 300 bedded hospital. 5ml sample was taken; centrifuged and complete lipid profile was done. Total cholesterol was measured by the CHOD-PAP method, Triglycerides were measured by the GPO-Trinder method, HDL-cholesterol measured by the Phosphotungstic acid method. The values of LDL and very-low-density lipoprotein cholesterol (VLDL) were be calculated using Friedewald’s equation Results: Among 50 screened patients, thirty five were males and 15 were females. The range of serum Cholesterol was from 69 mg/dl to 209 mg/dl with a mean of 130.02+/- 41.80. The range of VLDL Cholesterol was from 14 mg/dl – 93 mg/dl with a mean of 54.36+/- 17.35. The value of LDL Cholesterol ranged from 29 mg/dl to 120 mg/dl with a mean of 81.24+/-20.83. HDL Cholesterol ranged from 26 mg/dl- 98 mg/dl with a mean of 53.76+/-21.27. The range of Triglyceride was from 66 mg/dl-246 mg/dl with a mean of 132.72+/-48.06. Total lipids ranged from 390 mg/dl to 720 mg/dl with a mean of 550.28 +/-70.27.