Study Of The Association Of Antenatal Risk Factors In Children With Learning Disability

Research Article
Deepika Tiwari., Surbhi Rathi., Alka Subramanyam., Pooja Rathi and Santosh Kondekar
DOI: 
http://dx.doi.org/10.24327/ijrsr.2018.0903.1772
Subject: 
science
KeyWords: 
Learning disability, Antenatal risk factor
Abstract: 

Learning disability (LD) is a heterogeneous group of disorders manifested by difficulties in the acquisition of reading, writing, reasoning or mathematical abilities. A broad range of environmental risk factors may affect neurodevelopment, including prenatal causes like maternal use of alcohol, tobacco, or drugs, stress, advanced age, obesity, hypothyroidism, preterm birth. several epidemiological, obstetric adversities and prenatal risk factors associated with learning disability are either representing an epiphenomenon of the condition or derive from some shared risk factors, and their effect on neurodevelopment of fetus is collaborative effect of multiple interrelated pathophysiologies. Hence we decided to evaluate what is the burden of maternal risk factors over the causation of LD. Case control study was done with, sample size of 70 for both cases and controls. Mean maternal age in LD cases was 27.29 (with SD 4.69) with 7(10%) LD cases had history of advance maternal age at the time of conception. Pregnancy induced complications in mothers have highly significant association (p <0.01) in LD; among pregnancy induced complications most prevalence was Preeclampsia 13(18.57%) followed by anaemia 6(8.57%). Pre existing medical co morbidity had significant association with learning disability (p= 0.026), most prevalent was hypothyroidism 3(4.29%)