Varicose veins are a common cause of morbidity, etiologic factors predisposing to dilatation, elongation, and tortuosity of the saphenous vein and its tributaries are poorly understood. MMPs have a crucial role in the pathogenesis of VV, but limited work has been done in Indian population. The aim of this study is to study the levels of MMP9 in Varicose veins. A total of 74 control and 45 cases were included in the present study. The estimations of MMP-9 in Serum and Vein samples on comparison to Normal Individuals were not statistically significant. The levels of MMP-9 were at the upper limit of the normal ranges in patients of Varicose veins indicating that more studies on MMP’s as a measure of blood stasis in Varicose veins are needed to be performed in the future with different MMP’s and Advent of investigative modalities for the same.
