Background: Diabetes Mellitus (DM) is a group of metabolic diseases characterized by increased glucose level in blood. Type 1 DM usually accounts up to 10% of all diabetes cases whereas, Type 2 DM accounts up to 90% of all diabetes cases. DM can be fatal if proper treatment and care is not taken. Objectives: The aim was to evaluate the drug prescribing pattern of anti-diabetic drugs among diabetic patients. Method: Prospective observational study was conducted in the department of General Medicine and Endocrinology at a tertiary care teaching hospital. Data was obtained by medical records and patient interview and entered in suitable designed data collection form. Result: Out of 122 patients, 83% were type 2 DM patients and 17% were Type 1. Average drug per prescription was 4.25. Metformin in combination with glimepiride was prescribed commonly. Conclusion: Combinational therapy predominantly two drug therapy is a new trend in tackling diabetes mellitus.
