Malaria is a major health problem in India. It can be associated with many complications. Thrombocytopenia Is a common feature in malaria. In Patients having fever with thrombocytopenia, malaria should be on top of differential diagnosis. This was a study of admitted patients in Nandyal, rural area of Rayalaseema region of Andhra Pradesh, diagnosed with malaria and they were assessed for hrombocytopenia using automated quantitative D3 Analyzer .The data was analyzed using SPSS version 16.0. The results were obtained in numbers and percentages. Data was expressed as means with standard deviation. Viral hemorrhagic fevers can also present as fever but in these cases the complete blood counts has other features such as high hematocrit and leucopenia along with thrombocytopenia. Our finding can have therapeutic implications in the context of avoiding unnecessary platelet transfusion with the relatively more benign course in vivax malaria. In Our study the commonest cause of thrombocytopenia in malaria was vivax malaria.
