The high incidence of breast cancer is emerging as a major public health problem in Kerala. The prevalence of breast cancer in Kerala is much above the national average. It was reported that about 90 percent of the population in Kerala suffers from Vitamin D deficiency (VDD), which is more common in the affluent class and in some places in North Kerala where women wore dress which cover their bodies. The availability of Vitamin D is affected by various nutritional, physiological and environmental variables including cultural and traditional practices and use of Sunscreens with high Sun Protection Factor (SPF) above 15. The present study pursuits the association between Vitamin D and incidence of breast cancer. The study protocol was approved by IRB of Amala Institute of Medical Sciences, Kerala and signed informed consent was taken from the study subjects prior to the start of the study. Subjects who were newly diagnosed with breast cancer were selected using purposive sampling. Demographic and lifestyle variables of the subjects were collected by using suitably structured interview schedule. Biochemical variables like Serum Vitamin D, Calcium and oestrogen levels. SPSS version 24 was used for data analysis to find out Mean, standard deviation and correlation. Results of the study indicated that majority of breast cancer subjects were deficient with Vitamin D in which their life style factors played a role in making them deficient.
