We evaluated the effects of 12 genes polymorphisms on CAD(Carotid Artery Diseases) formation by using a ViennaLab CVD Strip Assay. Group A includes 41 patients (70.2 ± 8.6 years, 30 men) with CAD and Group B includes 39 healthy controls (67.3 ± 9.2 years, 28 men). Twenty patients had transient ischemic attack or stroke, 21 had carotid artery stenosis, more than 50 % in Group A. Hyperlipidemia is more frequent in Group A compared Group B (71%, 49%; p<0.05). Heterozygote form of Factor V H1299R, Factor XIII V34L, B-Fibrinogen -455G>A, MTHFR C677T and MTHFR A1298C were more frequent in Group A compared with Group B significantly [(2.6%, 7.3% p<0.05), (12.8%, 19.5% p<0.05), (12.8%, 19.5% p<0.05), (20.5%, 34.1% p<0.05), (25.6%, 46.3%p<0.05)]. The results of study showed that the formation of CAD, Factor V H1299R, Factor XIII V34L, B-Fibrinogen -455 G>A, MTHFR C677T and MTHFR A1298C heterozygous mutation seems to be determinant (p<0.05).
