The present study was designed to investigate the variations in lipid and lipoprotein cholesterol levels in fatty liver with or without alcohol intake. The main factors responsible for developing fatty liver were alcohol intake, type 2 diabetes mellitus, dyslipidemia and obesity. Fatty liver disease has been broadly classified into alcoholic fatty liver disease (AFLD) and non-alcoholic fatty liver disease (NAFLD). Extensive variations in lipid and lipoprotein cholesterol levels have been reported in fatty liver. It was observed that serum total cholesterol, serum triglycerides (TG), LDL-cholesterol and VLDL-cholesterol were increased and HDL-cholesterol was decreased in NAFLD and AFLD patients as compared to the controls. It was observed that change in mean serum lipid and lipoprotein cholesterol levels in all the groups of NAFLD when compared to each other were not significant (p>0.0001). All the subjects were evaluated for serum total cholesterol, serum triglycerides, serum HDL-cholesterol, LDL-cholesterol and VLDL-cholesterol
