Anticancer activity of Avicennia marina against HepG2 cell line was studied. During the present investigation, crude methanol extracts of A.marina were prepared using soxhlet apparatus. In vitro anti cancer activity of mangrove plant extracts at Eight different concentrations (7.8, 15.6, 31.2, 62.5, 125, 250, 500 and 1000 μg/ml) of methanol extract were applied against the chosen cell line using MTT assay (3-(4, 5-dimethylthiazol-2-yl)-2, 5-diphenyltetrazolium bromide). The various concentrations of methanolic extracts showed anti cancer activity. The most potent antitumor activity has been shown at concentrations 7.8 μg/mL and 500 μg/mL of methanol extract of A. marina on Hep G2 cell lines, respectively. The present study indicates that the methanolic mangrove plant extracts were effective against tumor cells and possess anticancer activity
