A prospective study was carried assessing the presence and evaluating the pathological role of antiphospholipid auto-antibodies (aPLA) in women suffering from unexplained infertility or recurrent first trimester abortion .It was carried out Between June 2013 and December 2014, on 20 women with unexplained fertility (group A), 20 women with recurrent first trimester abortion (group B), compared to 20 healthy women as control (group C). It was found that IgA, IgM and IgG levels were significantly higher in group A, B when compared to group C. Lupus anticoagulant (LA), tested by the activated partial thromboplastin time (APTT), was prolonged in 4 (20%) group A and 3 (15%) cases in group B. So it was concluded that reproductive performance may be affected by the abnormal presence of antiphospholipid auto-antibodies.
