Balanites aegyptiaca belongs to the family Zygophyllaceae. It is a common plants found in the several state of India. It is multibranched, spiny shrub or tree up to l0 m tall. Crown sphere-shaped, in one or several distinct masses. It contains saponin, furanocoumarin, and flavonoid namely quercetin 3-glucoside, quercetin-3-rutinoside; 3-glucoside, 3-rutinoside, 3- 7-diglucoside and 3- rhamnogalactoside of isorhamnetin Balanitoside. . Extraction was done by using soxhlet apparatus with 95% ethanol as the solvent. The mice were divided into four groups of six animals each comprising of Nomal Saline, Control group, A. Bilimbi Extract treated with Lower Dose (LD) (250 mg/kg b.wt) and Higher Dose (HD) 500 mg/kg b.wt). The study showed that A. bilimbi extract had prevention of chromosomal aberration
