An investigation into the accumulation of Lead, Arsenic, Zinc, Cadmium and Iron, in the sediment and the organs (gills, liver and flesh) of Tilapia species from Ureje Reservoir was undertaken. The sediment and fish parts were digested and analysed for the metals using Atomic Absorption Spectrophotometer.. The level of metal accumulation in the sediment followed this order Fe> Zn> Pb >As> Cd. Iron (Fe) was the most abundant metal present in the gills of the fish with the value (3.168± 0.03) for the month of June with a similar trend for the subsequent month which are July, August and September. The accumulation of metals were significantly higher (PZn>Pb>As>Cd. The most concentrated metal in the organs of the fish samples was iron. Fe, Zn and Pb were the three most abundant metals in the organs of these fishes and the same trend was also seen in the sediment. Cadmium and Arsenic were detected at low levels in the fish organs and the sediment samples. The heavy metals assessed were a little above WHO/FEPA standard limit which suggests that the reservoir could be polluted with heavy metals.