The targeted drug delivery system is designed to deliver the drug to the target site in reliable dose that should not affect the remaining tissue other than the target site. As a result, drug is localized on the targeted site. Hence, surrounding tissues are not affected by the drug. Thus, the carrier technology provides an approach for drug delivery, drug is coupled with a carrier molecule such as microspheres which take the drug at the target site and also modulate the release as well as absorption of drug from it. The core microspheres sustained the release for 10hrs in a pH progression medium mimicking the condition of GIT. Drug release studies microspheres were carried out in a similar dissolution media. In acidic medium the release rate of drug form the microspheres was very slow, but the drug was released fast at pH 7.4 and release was sustained up to 24 hrs.
