A case report on astroblastoma

Case Report
Dr. Kallu Praneeth, Dr. Sandeep Madineni, Dr.G Ramakrishna Reddy, Dr. Bandi Naveen Reddy, Dr. Ananth Egoor
DOI: 
http://dx.doi.org/10.24327/ijrsr.20251605.0053
Subject: 
Neuroradiology
KeyWords: 
Astroblastoma, Histogenesis, Immunohistochemistry, Differential diagnosis, Adjuvant radiotherapy.
Abstract: 

Background: Astroblastoma is a rare neuroepithelial tumor that often originates in the cerebral hemisphere of children and young adults. Diagnosis of this obscure neoplasm can be difficult because these tumors are so infrequently encountered and share common radiological and neuropathological features of other glial neoplasms.  Case Description: We present a case of a low-grade astroblastoma diagnosed in a 30-year-old female with complaints of headache, vomiting and vision changes. CT was done which revealed anintra-axial neoplasm in the left frontal lobe. Further CE MRI brain was done which showed a heterogeneously enhancing solid &cystic mass in the left frontal lobe with septationsand predominant cystic component. There was mild peritumoral edema. She underwent gross total resection. There was noevidence of high-grade features hence adjuvant therapy was not planned postoperatively. Conclusion: Astroblastoma is a very rare primary brain tumor. Its diagnosis is often challenging because of the astroblastic aspects that can be found in astrocytic tumors, in ependymomas, and in non-neuroepithelial tumors. Astroblastoma therefore must be considered in the differential of supratentorial tumors in children and young adults. Treatment of such, as suggested by most recent literature, includes gross total resection and adjuvant radiotherapy for lesions exhibiting high-grade features.