Case Report: Vildagliptin Induced Bullous Pemphigoid

Research Article
Arthanareeswaran S., Blessy Joy., Blessy Paulson., Chandini S Nair., Rajalakshmi J and Reshma Thomas
DOI: 
http://dx.doi.org/10.24327/ijrsr.2019.1006.3629
Subject: 
science
KeyWords: 
Blisters, Bullous Pemphigoid, DPP-4 inhibitors, Ulceration, Vildagliptin
Abstract: 

Bullous pemphigoid (BP) is an acquired autoimmune disorder characterized by chronic blistering of the subepidermal skin. BP is classified as type II hypersensitivity reactions and can be induced by drugs such as furosemide, nonsteroidal anti-inflammatory agents, DPP-4 inhibitors, captopril, pencillamine and antibiotics. Case of a 85 year old male is presented here. The patient was presented with the complaints of blisters on right and left leg for 2 days and also had a history of ulceration. The clinical diagnosis of BP was confirmed pathologically. After switching vildagliptin to insulin, remission was achieved.