Peripheral neuropathy is a common neurological disorder characterized by sensory disturbances such as pain, numbness, tingling, and loss of vibration sense, often associated with diabetes mellitus and degenerative changes. Conventional management focuses on symptomatic relief and is frequently limited by partial efficacy and adverse effects. Ayurveda describes peripheral neuropathy under conditions such as Vatavyadhi, PramehaUpadrava, and Vata-pradhanaNanatmaja Vyadhi. Brihat Vata Chintamani Rasa (BVCR) is a classical Ayurvedic mineral formulation indicated in chronic and severe Vata disorders involving the nervous system. This paper presents a single case of peripheral neuropathy managed with BVCR, demonstrating significant improvement in neuropathic pain, sensory deficits, vibration perception, functional capacity, and quality of life. The outcomes suggest that BVCR may serve as a promising therapeutic option in peripheral neuropathy when administered judiciously under Ayurvedic supervision.