Comparative Analysis Between The Gene Sequences Of The Major Histocompatibility Complex (Mhc) And The Antibody/ T- Cell Receptor Genes

The genes that code for major histocompatibility complex (MHC) molecules, the antibody (immunoglobulins) and the T-cell receptor occur in multiple forms which helps to create diversity. This review describes polygeny as seen in the MHC and the antibody/TCR genes and how they generate diversity. Also described is the organisation, gene structure, pattern of inheritance, and regulation of transcription of MHC and antibody/TCR genes. The differences and similarities between the MHC and antibody/TCR genes genes are also highlighted