Several studies demonstrated that the use of graft material has better clinical results for the treatment of intrabony defects. The purpose of this study is to compare the clinical and radiographic efficacy of alloplast (Biphasic calcium phosphate) and demineralized freeze-dried bone allograft (DFDBA) in treatment of periodontal intraosseous defects. A split mouth study was conducted in 20 subjects diagnosed with chronic periodontitis presenting atleast two intrabony defects in either arch. One quadrant (Site A) received alloplast (Biphasic calcium phosphate) and the contralateral defect (Site B) received DFDBA. The results of study showed that clinically Site B (DFDBA) showed greater reduction in pocket depth and gain in clinical attachment level than site A (Biphasic calcium phosphate), however it was not statistically significant. Site A (Biphasic calcium phosphate) showed slightly more gingival marginal recession than Site B (DFDBA). Radiographically Site B (DFDBA) showed greater bone fill compared to Site A (Biphasic calcium phosphate) which was statistically significant.
