Aim: Aim of this in vitro study is to ascertain whether immediate or delayed post space preparation would affect the apical seal obtained using two different root canal sealers. Materials and Methods: Seventy freshly extracted human permanent intact maxillary central and lateral incisors (anterior teeth) with straight and single patent root canals were decoronated, irrigated using 5% sodium hypochlorite & 17% EDTA; biomechanical preparation was done followed by obturation. The obturated teeth were randomly divided into 6 groups depending on the post space preparation time and obturation materials used. Group I and II: Immediate and delayed post space preparation respectively with Gutta percha/AH plus as obturating material. Group III and IV: Immediate and delayed post space preparation respectively with Gutta percha/Apexit Plus as the obturating material. Group V& VI served as positive & negative controls respectively and contained 5 teeth each. The samples were suspended in methylene blue dye, after which they were sectioned and measured & studied under stereomicroscope. Statistical Analysis The data was subjected to statistical analysis using Mann Whitney U test. Results: No statistically significant result was found between the two obturating materials for delayed post space apical leakage.
