Aim of the study: Our aim was to compare patients’ satisfaction and cooperation, and clinical efficacy, of midazolam alone, and midazolam and fentanyl citrate for intravenous sedation during day care minor oral surgical procedures.
Materials & methods: In this randomised, prospective study, forty patients who required day care minor oral surgical procedures were divided into two groups. In the first group, sedation was given with Midazolam and in the second group, combination of midazolam and fentanyl was given. Vital signs and oxygen saturation were recorded at every 5-minute interval during the procedure. Patients’ and surgeons’ satisfaction and the patients’ degree of amnesia about the local anaesthetic, drilling, manipulation of soft tissues were also assessed by giving 2 questionnaires to patient and one to the operating surgeon.
Results: Results of this study showed that no significant differences, both statistically and clinically, between systolic and diastolic pressures, heart rate, oxygen saturation were found. Patient satisfaction and patient cooperation was more with the combination group (p≤ 0.004) than with the other group.
Conclusion: Intravenous sedation using the combination of midazolam & fentanyl is a safe and reliable technique to perform minor oral surgical procedures in a day care setting. Both patient and the operating surgeon comfort was significantly improved without altering the vital signs of the patient to extreme levels.
