Aim & Objective: To compare the serum erythropoietin levels in subjects with generalized chronic gingivitis and generalized chronic periodontitis and to assess the anemic status in subjects with periodontitis. Materials & Methods: A total of 30 subjects with generalized chronic gingivitis (n=15) and generalized chronic periodontitits (n=15) participated in the study. Clinical parameters such as plaque index (PI), gingival index (GI), Probing depth (PD), Clinical attachment level (CAL) were assessed. For all these subjects, 2ml of venous blood samples were collected from anticubital fossa by a standard venepuncture method under aseptic conditions and assessed for the levels of Hemoglobin (Hb) and Erythropoietin (Epo) levels. Results: Clinical parameters were elevated in group-II (GCP) compared to group-I (GCG). Epo levels varied considerably between the two groups. Higher values of Epo were seen in Group II with Epo value- 53.132 mIU/ml compared to group-I with Epo value- 39.10 mIU/ml. The haemoglobin levels in subjects with GCG was 11.48 gm% and in subjects with GCP was 10.99 gm%. Conclusion: Erythropoietin is an important marker of periodontal disease and aids to assess the anemic status in subjects with periodontitis
