Comparison Of Symptoms, Signs And Haematological Parameters In Dengue Patients Admitted In A Tertiary Care Centers In Kolkata, 2014 And 2012 Epidemic

Research Article
Ashis Kumar Saha and Payodhi Dhar
DOI: 
xxx-xxxx-xxxx
Subject: 
Medicine
KeyWords: 
Symptoms and signs, Dengue fever and dengue hemorrhagic fever, Kolkata, West Bengal.
Abstract: 

Dengue fever may present as subclinical infections, mild uncomplicated dengue fever or complicated dengue fever in the form of dengue hemorrhagic fever (DHF) and dengue shock syndrome (DSS). On and from the first incidence of dengue fever in 1824, six epidemics occurred in 1836, 1906, 1911, 1923, 2005 and 2012 in West Bengal. Our aim was to compare clinical and hematological profile between males and females as well as to compare the data with that of patients admitted in a tertiary care center in Kolkata throughout their hospital stay. Total 404 patients having either non structural (NS1 ) antigen positive and/or immunoglobulin M dengue antibody positive were admitted in our hospital. Just after admission, proper history and examinations were performed, this was followed by drawing of blood for hematological and biochemical examinations. Within 24 hours, imaging studies in the form of ultrasound of upper abdomen and chest x-ray were performed. Above hematological and biochemical tests were repeated after 48 hours. After collection of all the data, we made comparisons of these collected data between males and females. Number of DHF and DF patients was 295 and 109 respectively having following significant symptoms, like, fever, nausea/vomiting, headache and backache and evidence of plasma leakage (in DHF patients). Females were anemic with low hematocrit value. 69.05% patients were leucopenic. During admission, 201 dengue patients (49.75%) were thrombocytopenic, but the number was increased to 295 (73%) during the course of illness. Male to female ratio was 1.34:1. Of 404 patients, 73% patients suffered from DHF. Commonest presentations in this study were fever, nausea/vomiting, backache and headache. Females were mainly anemic with low hematocrit value. Significant number of patients was leucopenic. Small number of patients showed evidence of plasma leakage.