Suicide is one of the major psychiatric problems. About 800,000 people commit suicide every year. Suicide is preventable but, we failing due to lack of theory and concepts about suicide13. There are few theories about interpersonal factors, symptoms of suicide etc. In this conceptual framework we linking between the risk factors, signs of suicide, Lines of Defense and suicide. The risk factors are common among most of the people but our coping mechanism helps in maintain the equilibrium. Some people show Warning Signs we assume that its coz of the failure of coping mechanism which we use on daily basis. Defense mechanism is the final line of defense that prevents attempting suicide. By Knowing this linage we can have a better direction towards prevention of Suicide.