Correlation Of Mucocutaneous Manifestations With Cd4 Count In Hiv Infected Patients In Tertiary Care Hospital

Research Article
Deshpande P N and Smita Chakote
DOI: 
http://dx.doi.org/10.24327/ijrsr.2019.1007.3737
Subject: 
science
KeyWords: 
CD4 count, HIV, Mucocutaneous manifestations
Abstract: 

While there are other parameters for prediction of progression of HIV, mucocutaneous manifestations of HIV are considered among key clinical indicators for prediction of underlying degree of immunosuppression. 175 HIV infected patients were included in this study. Demographic parameters such as age, gender, occupation, educational status, family history were recorded. Laboratory parameter (CD4 counts) and treatment regimen were noted. Patients were examined for mucocutaneous manifestations by a dermatologist. Data was analyzed using chi-square test for categorical variables. Mean CD4 cell count of asymptomatic HIV patients was 499.85 cells/mm3 , compared to 480.62 cells/mm3 in symptomatic HIV patients. This was correlated using student t‑test and was statistically significant (P=3.88). Maximum number of cases were observed in CD4 count range of (200-500) cells/mm3 .CD4 count was significantly less in Symptomatic cases than in asymptomatic cases. Thus mucocutaneous manifestations can give clue to suspect the diagnosis of HIV infection in an otherwise healthy patient.