
Periodontal disease is characterized by numerous clinical and radiographic features. Infrabony defects are a common finding in progressive periodontal disease. Numerous regenerative procedures with promising results have been developed for the purpose of treating such defects. Since there are several techniques, a combination of these have been tried to enhance the outcome of the treatment. Guided tissue regeneration is a procedure that involves placement of a barrier membrane to help repopulate regenerative cells in an attempt to re-grow lost cementum, periodontal ligament and alveolar bone. Bone grafts have been used to fill infrabony defects caused due to periodontal destruction. These grafts mineralize to form normal bone over a period of time. Guided tissue regeneration in combination with the use of demineralized bone grafts have been used in a regular basis to achieve increased success in treating periodontal defects. The following case report shows a case of a 10mm infrabony defect treated successfully with a combination of guided tissue regeneration and demineralized bone graft.