India is one of the countries where the highest cases of dengue fever are reported. The number of patient and distribution area increases with increasing mobility and population density. Carica papaya L. belongs to Caricaceae family is a widely cultivated plant in India. The leaves of papaya are believed to boost platelet count and dengue fever patient benefit, but there are few limited work has been done by scientists on this. The objective of this study was to determine the effects of C. papaya leaves extract (CPE) on dengue fever patient. The study was designed with 120 subjects, which includes 80 dengue patients and 40 healthy subjects. Subjects are divided into three groups control, dengue patient and CPC treatment group. Treatment group was given 50g/day CPE up to 3 days. The results indicated that CPC group had maintained stability of hematocrit in the normal level, shorten hospitalization period and increased the platelet count significantly in dengue fever patients as compare to the control group
