Background: Leptospirosis is a zoonotic spirochetal disease. The spectrum of human disease is ranging from subclinical infection to a severe syndrome of multiorgan infection with high mortality. Aim: To evaluate the epidemiological factors & the clinical presentation. Method: Patients with fever admitted in a GMC, Surat, Gujarat who were tested positive for Leptospirosis were evaluated for epidemiological risk factors in addition to the clinical profile. Result: Total 326 patients are evaluated. The peek time was rainy season and harvesting, farmers are most affected. Males were more than females. In the clinical spectrum, fever is present in all, followed by jaundice, myalgia, oligouria and haemorrhage. Conclusion: Rain-fall is the main epidemiological factor followed by harvesting of crops & Poor knowledge regarding mode of transmission by farmer is the main reason behind the occurrence of disease.