Introduction: Obesity leads to an increased risk of cardiovascular disease both as an independent factor and by causing metabolic disorders such as hepatosteatosis, hypertension, dyslipidemia, and insulin resistance. Changes in platelet indices have a significant impact in thrombotic and prethrombotic events. In our study, we aimed to evaluate platelet indices such as the platelet count (PLT), mean platelet volume (MPV) and platelet distribution width (PDW) that have a role in the atherothrombotic process and to investigate their relationship with lipid profile tests such as total cholesterol, triglycerides, HDL-cholesterol and LDL-cholesterol in obese adolescents with hepatosteatosis. Methods: We gathered data by retrospectively investigating the files of 68 patients aged 10-16. Adolescents with a body mass index (BMI) at or above the 95th percentile according to age and gender were described as obese.Patients were split into three groups based on USG results as following: obese adolescents with hepatosteatosis, obese adolescents without hepatosteatosis, and control group of healthy adolescents. The groups were compared in terms of laboratory tests, gender, age, and BMI. The data were statistically evaluated usingSPSS software package. Results: PDW values of the obese group with hepatosteatosis were statistically significantly lower than those of the healthy control group (p=0.017; p0.05). There was a significant positive correlation betweenPLT and total cholesterol, and LDL-cholesterol (p<0.05). Conclusion: Obese adolescents with hepatosteatosis had lower PDW levels. On the other hand, PLT and MPV levels had no relationship with obesity and hepatosteatosis in adolescents. Moreover, the positive correlation betweenPLT, total cholesterol, and LDL-cholesterol indicates that platelets and lipids might have a cooperative role inatherothrombotic complications in obese adolescents with hepatosteatosis.
