Background: Breast cancer is the most common cancer in women and is the leading cause of cancer death. Breast cancers are predominantly sporadic, but family aggregation has been found in about 20% of cases. The objective of this work is to estimate the prevalence of familial breast cancer and to describe the epidemiological, clinical and prognostic characteristics of patients with a family history of breast cancer, treated at the Mohammed VI center for cancers treatment, CHU IbnRochd Casablanca. Patients and methods: A cross-sectional study carried out within the Mohammed VI Center during the year 2014. The data were collected from patients' medical records and analysed by the Epi Info software. Results: 13.6% (89/655) of the cases had a family history of breast cancer, 46.1% of cases of the first degree, 24.7% of the second degree and 29.2% of the third degree. The mean age at diagnosis was 46.8 ± 10.1 years. The stage at diagnosis was in most cases early (66.3%) and late in 33.7% of cases. Tumour size was in 39.3% of cases T1, 36.0% T2, 12.4% T3 and 9.0% of T4 cases. The involvement of lymph nodes (N) was in 57.3%, 6% N1, 12.6% N2 and 4.4% N3. Remote metastasis (M1) was observed in 4.5% of cases. Conclusion: familial breast cancer represents 13.6% in our center, diagnosed at a young age and a stage at the time of the early diagnosis. These results are consistent with several studies in America and Europe. In addition, in the presence of a family history of breast cancer, screening and genetic counselling should be done to clarify the incidence of expectations in familial oncology.
