
Fungi are the diverse group of saprophytic and parasitic eukaryotic organisms. Now placed in kingdom Mycota. Fungi produce and secrete a variety of metabolic products. They are toxic to animals and humans. Fungi cause poisoning and infections. Pneumocystis is the cause of lethal pneumonia of immunocompromised patients. Previously, considered this as a parasite but now included in fungi. Aspergillosis in immunocompromised patients, leukemia patients and bone marrow transplant patients produce serious complications and finally death. Candida albicans produce diaper rash, oral thrush, vulvoveginitis. Histoplasma produce progressive pulmonary disease similar to pulmonary T.B. Blastomycosis produce skin lesions. In AIDS patients cryptococcosis, the second most common fungal infection (After candidiasis) is potentially most serious. Fungus is sophisticated than virus and bacteria They have cell walls, but lower than plant and animal(1). During this period several fungi such as Actinomyces, Candida albicans, Crytococcus neoformans, were isolated, cultured, identified and described(2)