Urinary stone disease is one of the major diseases in the human history. The human urinary calculi are mainly formed from calcium oxalate, Struvite and uric acid crystals. It is important for the physician and surgeon to distinguish the two types of hydrates of calcium oxalate mainly mono and di-hydrate. Manganese doped Calcium Oxalate Monohydrate (MnCaOxM) crystals were grown by silica gel method. Manganese is a trace mineral that is present in tiny amounts in the body. It is found mostly in bones and blood clotting factors. It is also plays a role in fat and carbohydrate metabolism. Manganese is also necessary for normal brain and nerve function. The grown crystals were characterized by FTIR, FT-Raman XRD, SEM-EDX, TGA/DTA analysis and UV-Visible analysis.