Histomorphological Patterns Of Dysfunctional Uterine Bleeding On Endometrial Biopsies- Revisited

Research Article
Sushma Shankar and Nataraju G
DOI: 
http://dx.doi.org/10.24327/ijrsr.2018.0904.2027
Subject: 
science
KeyWords: 
Dysfunctional uterine bleeding: Endometrial biopsy; Proliferative endometrium
Abstract: 

Background-Dysfunctional Uterine Bleeding (DUB) is defined as abnormal uterine bleeding not caused by pelvic pathology, medications, systemic disease or pregnancy. It is a diagnosis of exclusion. Endometrial biopsy is a simple, cost effective procedure which helps in ruling out organic causes and establishing the changes in endometrium. Objectives-To analyse the endometrial histomorphological patterns in cases of DUB and to correlate with clinical presentations. Methodology-Endometrial biopsy samples fixed in 10% formalin were processed, embedded, sections cut, stained with H& E stain and hisopathological features were noted. Results- Out of 500 endometrial biopsies studied, 225 were Proliferative,69 Secretory,127 Simple hyperplasia without atypia,27 Complex hyperplasia without atypia,10 Mixed endometrium,07 disordered proliferation,07 chronic endometritits,05 Partial mole,05 luteal phase defect,05 atrophic,04 Arias stella reaction,04 inadequate,02 Endometrial adenocarcinomas, 01 endometrial stromal sarcoma and01 Endometrial polyp. Majority of patients were in the age group of 31-40 years. Most common presenting complaint was menorrhagia. Conclusion-The study helps in detecting and differentiating functional causes from organic lesions, thereby facilitating appropriate patient management