Introduction: Infection control measures are the focus of quality care by health care sector, as control of health care associated infections will improve the morbidity status and can also prevent mortality. Periodic review of health care personnel’s in this regard will go a long way in identifying weakness and strengthening them. Therefore this study was taken up to measure the awareness, practice, attitude and hand hygiene measures related to infection control and test the role of practice based intervention program among health professionals working medical and surgical units of multispecialty hospitals. Methods: The research approach adopted for the study was quantitative approach. Purposive sampling was done and 30 health professionals were selected for the study. Self-administered questionnaires on Knowledge, attitude, infection control and Observational check list related to infection control measure compliance and infection control practice were used to collect data. Results: The overall pretest and posttest mean knowledge of only nurses was found to be 17.2+5.20 and 37.2+2.78 respectively indicating the enhancement knowledge significantly (p =0.01). Even practice and attitude also significantly improved suggesting that practice based intervention programme was impactful among nurses. The findings on The other health professional- other professionals’ infection control practice scores (87.7+5.31) seemed to be slightly better than that of nurses (84.4 +9.02). But the knowledge was average and attitude seemed to be good. Hand hygiene practices were good among both nurses and other health professionals. Discussion & Conclusion: over all the in infection control knowledge level of nurses and other health professionals was just adequate compared to their good practice scores. The training programme was effective in improving the over-all score of the nursess related to the knowledge, attitude, and practice regarding infection control. Even other health professionals other professionals, surgeon, interns knowledge, practice was not high. Thus, it can be propose to train the all levels of health professionals on various aspects of infection control and introduce an on-going training program in the curriculum.
