Zika virus is an arbovirus, member of the Flaviviridae family of genus Flavivirus, which also includes dengue, yellow fever, and West Nile viruses. It was first identified from rhesus macaques in the Zika forest near Kampala, Uganda in 1947. Zika virus has two major lineages: Asian and African. In Africa, it is thought to revolve between non-human primates and mosquitoes, with humans as accidental hosts. However, humans have been probably the main hosts in areas outside the Africa. The key vector for Zika virus transmission is thought to be the daytime biting mosquito Aedes aegypti and Aedes albopictus. Infection with Zika virus results in fever, rash, conjunctivitis, arthralgia, and myalgia, or it may be subclinical. Zika fever in pregnant women is associated with microcephaly
