A study examining the association of Entamoeba histolytica infection with anemia was conducted. A total of 44 children aged two months to twelve years-old were studied. Data were collected using structured questionnaires, anthropometric measurements and laboratory analysis of blood and stool samples. Analysis of the results showed that 65.90% of children were infected with E.histolytica, as well as significant differences were found among children with and without E.histolytic in Body Mass Index (P=0.02994), ferritin (P=0.00000649) and serum iron (P=0.00000311). E.histolytica infection was statistically correlated with iron deficiency anemia in this study population results showed that 13.79 % of infected children were considered to have iron deficiency anemia 65.51 % of infected children were at risk of iron deficiency anemia while no child of the non infected group was considered to have or were at risk of iron deficiency anemia
