Introduction: Lifestyle influences the self-efficacy of family parents and decision-making regarding the treatment of chronic diseases. This study describes the relationship between self-efficacy (AU) and lifestyle (EV) of those without (n1) and with (n2) Type 2 diabetes (T2D), and describes the difference between the means of the EV in both groups. The framework was Pender's Health Promotion model (Pender, 2006). Methodology: The design of the study was descriptive, transversal, correlational and comparative, the sample was collected in a rural area of Puebla, Mexico, it was nonprobabilistic with 312 participants (n1 = 151, n2 = 161). Results: For n1 the average age was 40.15 years (S.E.± 8.16), where 71.5% were women, the correlation between lifestyle and self-efficacy was defined by r = 0.222, p≥0.01, accounting for 4.9% of the variance (R2 = 0.049), and the n2 the average age was 57.3 years (S.E.± 9.8), where 70.6% were women, with an r = 0.382 (p≤.001) between self-efficacy and lifestyle, accounting for 14.6% of the variance (R-Squared = 0.146), the t test was -4.153 (p≤.001 so there were no differences in the EV of both groups. Conclusions: The correlations were positive and statistically significant, it follows that self-efficacy favors the adoption of a better lifestyle, confirming what Pender model (2006) promulgates. There is no difference between the lifestyle of family parents with and without T2D coinciding with Mellado (2011) Gamarra, et al (2010), Angulo et al (2014). These findings confirm that the promotion of self-efficacy in family parents with and without T2D improves their lifestyle, with which risks and complications of the disease will be reduced.
