Introduction: Prediabetes or impaired fasting glycemia or impaired fasting glucose (IFG) refers to a condition in which the fasting blood glucose is elevated above what is considered normal levels but is not high enough to be classified as diabetes mellitus. Nearly 70% of prediabetes subjects can eventually develop diabetes if not managed in early stages. Both IFG and IGT (Impaired glucose tolerance) are associated with increased cardiovascular risk due to impaired Dyslipidaemia. Aim: To study lipid profile in prediabetic subjects. Material and Methods: 100 cases and 100 controls were compared for the lipid profile. Duration of study was from June 2017 to June 2018. Subjects were enrolled after applying all inclusion and exclusion criteria. This was a cross sectional case control study. Results: The prediabetic subjects had significant increase in serum total cholesterol, TG, LDL, VLDL, TG/HDL and LDL/HDL ratio compared to normal healthy subjects while HDL was significantly decreased in prediabetic as compared to normal healthy subjects. Conclusion: Prediabetic subjects had significantly deranged lipid profile values. Due to dyslipidemia, they are highly prone for cardiovascular and microvascular complications. We recommend that proper screening of prediabetic for dyslipidemia can prevent early cardiovascular and microvascular complications. We also suggest lifestyle changes and pharmacotherapy for prediabetes subjects to prevent the risk of cardiovascular and microvascular disease.
