In this study, we investigate the drought pattern in Qinghai Province for the period between 1961 and 2013. Utilizing the monthly precipitation data of 32 stations and adopting the Standardized Precipitation Index (SPI), we explore the possible drought events in Qinghai Province over the past 53 years. We find a high frequency of drought in the Qinghai Province (on the basis of 12-month SPI index) in 1962, 1966-1967, 1970, 1973, 1986, 1992-1993, 1996 and 2001-2004. We demonstrate that some areas in the eastern Qinghai (including Mangya, Lenghu, Xiaozaohuo, Dachaidan, Ge’ermu, Wudaoliang, Nuomuhong and Tuoyuohe) are changing from humid to drought climate. On the other hand, most of the eastern part of Qinghai Province is changing to humid environment. We demonstrate that the drought is persistently occurring in Qinghai Province with prolonged periods. The degree order of seasonal-SPI drought index in Qinghai Province is: maximum in summer followed by autumn, spring and winter. Findings of this study have significant implications for setting up adaptation and mitigation strategies related to forest and natural resources.