Morphological analysis of pulmonary lesions in autopsied patients at a tertiary healthcare center

Research Article
Arpita J. Nishal, Komal K. Patel*, Deepshikha P. Dave, Heer D. Dabhi, Hinaben H. Kakadiya, Suresh G. Padsala
DOI: 
http://dx.doi.org/10.24327/ijrsr.20251603.0025
Subject: 
Pathology
KeyWords: 
Lung autopsy, Histomorphological pattern, Pneumonia, Tuberculosis
Abstract: 

Introduction:Lungs are vital organs involved in various diseases like infectious, inflammatory, nonneoplastic,neoplastic lesions and involved secondarily in almost all forms of terminal diseases. The lungs are also involved in almost all terminal events of cardiovascular disease. As pathological examination of lungs gives valuable information, autopsy is performed to know the distribution and progression of diseases and to detect undiagnosed lung diseases. Aims and objectives:To study histomorphological pattern and frequency of pulmonary lesions encountered in lung autopsies. Materials and methods: This study is a retrospective study done in the autopsy section, department of pathology, government medical college, surat over a period of 1 year from January-December,2022. The cases were investigated for lung pathology. Results:After thorough histopathological examinations, of total 945 cases, various pulmonary lesions were identified in 446 cases.  393 out of 446 cases were males(88%), while 53 were female(12%). Most commonly affected age group was 41-50 years  113 cases(25.33%) followed by 31-40 years 101 cases(22.64%). In the present study, non neoplastic lesions were more common. Most common was pulmonary edema in 218 cases(48.87%). Other were pneumonia(27.57%),alveolar hemorrhage(22.86%), chronic venous congestion(11.88%) and tuberculosis(8.96%). Rare lesions reported were adenocarcinoma, squamous cell carcinoma and non-hodgkins lymphoma. Conclusion: In our population, the present study reveals that infectious disease are still the most common cause of mortality, despite recent advances in diagnostic technology. Post-mortem examination of diseased lung offers the chances to establish a diagnosis and help us to confirm an uncertain antemortem diagnosis.