Mosquitoes are transmitting several diseases such as malaria, dengue, yellow fever, West Nile virus fever, Japanese encephalitis, filariasis and, more recently, Zika virus. Mosquitoes are the major vector for the transmission of several communicable diseases and causing millions of deaths every year. The eco-friendly control of mosquito vectors is a crucial challenge of public health importance. Therefore, the present study was aimed to investigate the mosquito larvicidal activity of hexane, diethyl ether, dichloromethane, ethyl acetate and methanol extract of AristolochiaindicaLinn. (Aristolochiaceae) against vector mosquito Ae.aegypti, An. stephensi and C. quinquefasciatus. The larvicidal bioassay test was assessed under laboratory condition and experiments was designed according to the standards protocol. The larvicidal activity of leaf extracts of Aristolochiaindica was tested with 100 -500ppm concentrations against fourth instar larvae selected mosquitoes. The LC50and LC90value of hexane, diethyl ether, dichloromethane, ethyl acetate and methanol extract of Aristolochiaindica were 260.80, 257.64, 255.88, 260.77, 261.06, 259.33, 263.98, 265.08, 173.45, 251.01, 256.31, 246.79, 226.59, 226.42, 230.05 and 462.57, 471.23, 464.96, 468.65, 470.83, 465.24, 465.25, 467.16, 379.42, 445.49, 461.26, 446.10, 426.56, 421.43 and 421.39Ae. aegypti, An. stephensi and C. quinquefasciatus respectively. Among the different extracts tested methonal extracts showed maximum activity against selected mosquitoes.
