The simultaneous occurrence of multiple cysts in both the jaws of a patient is rare and it usually occurs as the manifestation of a syndrome. Whenever multiple cysts are found, it is necessary to rule out an association with any syndrome, as the chances of recurrence are very high and a periodic follow-up is required for such patients. In our patient, cyst enucleation was done previously, but the association with the Gorlin-Goltz syndrome was missed and no follow-ups were advised. Gorlin and Goltz first described the spectrum of features which are associated with the Gorlin-Goltz syndrome or the Nevoid Basal cell carcinoma syndrome (NBCCS), in 1960. It is an autosomal dominant disorder with a genetic locus on chromosome subbands and bands 9q22.3-q31.1 It comprises of skeletal features such as the bifid rib, frontal and parietal bossing and mandibular prognathism and cutaneous abnormalities such as multiple basal cell carcinomas and palmar and plantar keratosis. NBCCS can also include concomitant hypertelorism, mental retardation, strabismus, calcification ofthe falxcerebri and medulloblastomas.2 We are discussing here a case of two mandibular cysts withexpression of many of the features of NBCCS and are briefly reviewing the features of the Gorlin-Goltz syndrome.
