Three or more consecutive miscarriages before 20 weeks of gestation is considered as recurrent miscarriage (RM). It is a challenge for obstetricians to handle these sensitive issues which involves not only wife but also the whole family. Though recurrent miscarriage is multifactorial genetic contribution plays important role in causing recurrent miscarriage. Numerical and structural aberrations in chromosomes become the causative factor in recurrent miscarriage. Polymorphic variations are seen to be associated with RM. To find out whether Y chromosomal polymorphic variations play role in recurrent miscarriages 339 couples (678 patients) of history recurrent miscarriages were analyzed by karyotyping. Out of 339 patients in 33 (8.2%) patients Y chromosomal polymorphic variations were noticed. Amongst 33 patients in 6 (1.7%) cases Yqh+, in 21 (6.7%) Yqh-, in 5 cases inversion Y (1.2%) was found.
