It can be noticed, recently, the important role of information system to enhance the life style of people with disability. Therefore, it can be motivating for all researchers to set a road map for developing and designing special system for them. For this reason, the authors present this article as a first step to develop a new health system for Down syndrome and increasing the role of information technology by setting a new taxonomy for individuals with Down syndrome based on their needs of healthcare services. The methodology of this study is to present a short introduction of Down syndrome and the role of the World Health Organization. Followed that, conducting literature review to cover and identify the common health problems that faces individuals with Down syndrome. Finally, present the proposed taxonomy for these individuals.
