Aim- To check the efficacy of Astragalus extract against Streptococcus mutans and Candida albicans
Methodology- In this in vitro Microbiologic study was done using Mitis Salivarius agar media (for S.mutans), Sabouroud Dextrose agar media (for Candia albicans ) for selective growth of different microorganisms via Kirby Bauer disk diffusion method. Freshly prepared media was used and allowed to dry, over that microorganism was taken from the prepared strains of Streptococcus mutans and Candida albicans which was streaked uniformly over medias, after that paper discs which were dipped overnight in the prepared Astragalus extract solution, Chlorhexidine solution and distilled water were placed over media and labelled 1, 2 & 3 respectively. After 24 hours of incubation the medias were checked for zone of inhibition.
Result- Astragalus showed good anti-microbial activity against S. mutans and its activity was somewhat similar to that of chlorhexidine in relation to S. mutans and even more effective in some samples, but astragalus’ activity against C. albicans is relatively less effective although it provides certain amount of anti-microbial action against it too
Conclusion- Astragalus inclusion in diet or in oral hygiene practices methods such as an ingredient in dentifrices or in mouthwashes can prove to be beneficiary. Its antimicrobial efficacy in addition to number of other contributory effects such as anti-inflammatory, anti-carcinogenic, immunomodulatory actions can enhance the host response.
