Introduction: The oral health education can be delivered through various ways where in the education imparted in schools has a major contribution towards the healthy mouth of the children. Thus the present study was undertaken to assess the effectiveness of various health education methods on school oral health knowledge and plaque status among the high school children in Piparia Village, Vadodara, Gujarat. Methodology: A cluster randomized control study was conducted at six schools at Piparia, Vadodara. Each of the six schools was given same education on oral health but in different ways. The score at baseline and after giving health education was calculated using sillness and loe plaque index score. Results: The overall mean knowledge score is 6.085±1.72. The baseline plaque score is 2.005±0.49. The increase in knowledge after the oral health education was increased to 8.07±1.93 and the plaque score decreased to 1.39±0.33. There is a significant increase in the knowledge score of 1.985 after the interventions (p value=0.006) and significant decrease of 0.615 in the plaque score after the interventions. (p value=0.0054). Conclusion: The study indicates that oral health education is effective in increasing the knowledge and awareness regarding maintenance of good oral hygiene. The oral health education should be the prime focus of the society for promoting the good oral health.
