Occupational Stress is defined in terms of its psychological and physiological effects on a person (or thing. Stress is mental, physical or emotional strain or tension or it is a situation or factor that can cause this. Work-related stress is now generally acknowledged a global issue in all professions and all workers in all countries. It is also widely acknowledged that it has a high cost in terms of human distress and impaired productivity. Stress can undermine the achievement of goals, both for individuals and for organizations. While it will not be possible for organizations to remove all these stressors it is important that they work with employees and managers to identify which aspects of the working environment are causing most difficulties and work together for improvements. As Occupational Health aims at the promotion and maintenance of the highest degree of physical, mental and social well-being of all workers in all occupations, patterns of prevention have to be devised and implemented to face the challenges that a changing world of work is bringing. Increasing emphasis has to be placed on improving working conditions and work organization in relation to stress at work and on practical measures to cope with stressful work situations. This article presents some strategies to prevent and reduce stress both at the organizational level as well as individually. The occupational stress problem in India is still an open question, waiting to be solved.